Identification of novel growth factor-responsive genes in neuroendocrine gastrointestinal tumour cells

@article{Hofsli2005IdentificationON,
  title={Identification of novel growth factor-responsive genes in neuroendocrine gastrointestinal tumour cells},
  author={Eva Hofsli and Liv Thommesen and Fekadu Yadetie and Mette Langaas and Waclaw Kusnierczyk and U G Falkmer and Arne K. Sandvik and Astrid Laegreid},
  journal={British Journal of Cancer},
  year={2005},
  volume={92},
  pages={1506 - 1516}
}
Targeting growth-regulatory pathways is a promising approach in cancer treatment. A prerequisite to the development of such therapies is characterisation of tumour growth regulation in the particular tumour cell type of interest. In order to gain insight into molecular mechanisms underlying proliferative responses in neuroendocrine (NE) gastrointestinal (GI) tumours, we investigated gene expression in human carcinoid BON cells after exposure to gastrin, hepatocyte growth factor (HGF), pituitary… CONTINUE READING
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