Identification of novel genes associated with HIV-1 latency by analysis of histone modifications

@article{Kim2017IdentificationON,
  title={Identification of novel genes associated with HIV-1 latency by analysis of histone modifications},
  author={Kyung-Chang Kim and S. Lee and Junseock Son and Younghyun Shin and C. Yoon and C. Kang and Byeong-Sun Choi},
  journal={Human Genomics},
  year={2017},
  volume={11}
}
  • Kyung-Chang Kim, S. Lee, +4 authors Byeong-Sun Choi
  • Published 2017
  • Biology, Medicine
  • Human Genomics
    • BackgroundA reservoir of HIV-1 is a major obstacle in eliminating HIV-1 in patients because it can reactivate in stopping antiretroviral therapy (ART). Histone modifications, such as acetylation and methylation, play a critical role in the organization of chromatin domains and the up- or downregulation of gene expression. Although many studies have reported that an epigenetic mechanism is strongly involved in the maintenance of HIV-1 transcriptional latency, neither the epigenetic control of… CONTINUE READING
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    References

    SHOWING 1-10 OF 35 REFERENCES
    Genome-wide analysis of histone modifications in latently HIV-1 infected T cells
    • 23
    • PDF
    Epigenetics of HIV infection: promising research areas and implications for therapy.
    • 24
    Regulation of HIV-1 latency by chromatin structure and nuclear architecture.
    • 41
    NF‐κB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation
    • 402
    • PDF
    The regulation of human immunodeficiency virus type-1 gene expression.
    • 122
    Chromatin disruption in the promoter of human immunodeficiency virus type 1 during transcriptional activation.
    • 440
    CpG methylation controls reactivation of HIV from latency
    • 210
    A compilation of cellular transcription factor interactions with the HIV-1 LTR promoter.
    • 375
    • Highly Influential
    • PDF
    Paucity of HIV DNA Methylation in Latently Infected, Resting CD4+ T Cells from Infected Individuals Receiving Antiretroviral Therapy
    • 66
    • PDF
    C/EBP activators are required for HIV-1 replication and proviral induction in monocytic cell lines.
    • 113