Identification of novel functional TBP‐binding sites and general factor repertoires

@article{Denissov2007IdentificationON,
  title={Identification of novel functional TBP‐binding sites and general factor repertoires},
  author={S. Denissov and M. V. van Driel and R. Voit and Maarten Hekkelman and Tim Hulsen and N. Hernandez and I. Grummt and R. Wehrens and H. Stunnenberg},
  journal={The EMBO Journal},
  year={2007},
  volume={26}
}
Our current knowledge of the general factor requirement in transcription by the three mammalian RNA polymerases is based on a small number of model promoters. Here, we present a comprehensive chromatin immunoprecipitation (ChIP)‐on‐chip analysis for 28 transcription factors on a large set of known and novel TATA‐binding protein (TBP)‐binding sites experimentally identified via ChIP cloning. A large fraction of identified TBP‐binding sites is located in introns or lacks a gene/mRNA annotation… Expand
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