Identification of novel ciliogenesis factors using a new in vivo model for mucociliary epithelial development.

@article{Hayes2007IdentificationON,
  title={Identification of novel ciliogenesis factors using a new in vivo model for mucociliary epithelial development.},
  author={Julie M. Hayes and Su Kyoung Kim and Philip Barron Abitua and Tae Joo Park and Emily R Herrington and Atsushi Kitayama and Matthew W. Grow and Naoto Ueno and John B. Wallingford},
  journal={Developmental biology},
  year={2007},
  volume={312 1},
  pages={115-30}
}
Mucociliary epithelia are essential for homeostasis of many organs and consist of mucus-secreting goblet cells and ciliated cells. Here, we present the ciliated epidermis of Xenopus embryos as a facile model system for in vivo molecular studies of mucociliary epithelial development. Using an in situ hybridization-based approach, we identified numerous genes expressed differentially in mucus-secreting cells or in ciliated cells. Focusing on genes expressed in ciliated cells, we have identified… CONTINUE READING