Identification of novel anthrax toxin countermeasures using in silico methods.


Anthrax is an acute infectious disease caused by the spore-forming, gram-positive, rod-shaped bacterium Bacillus anthracis. The anthrax toxin lethal factor (LF) is the primary anthrax toxin component responsible for cytotoxicity and host death and has been a heavily researched target for design of postexposure therapeutics in the event of a bioterror attack… (More)
DOI: 10.1007/978-1-62703-342-8_12


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