• Corpus ID: 73669112

Identification of novel PPARγ agonist from GC-MS analysis of ethanolic extract of Cayratia trifolia (L.): a computational molecular simulation studies -

@article{Perumal2014IdentificationON,
  title={Identification of novel PPAR$\gamma$ agonist from GC-MS analysis of ethanolic extract of Cayratia trifolia (L.): a computational molecular simulation studies -},
  author={Palanisamy Chella Perumal and S. Kamath Sowmya and Prabhakaran Pratibha and Balasubramanian Vidya and Palanirajan Anusooriya and Thangarajan Starlin and Ramasamy Vasanth and D. Jeya Sundara Sharmila and Velliyur Kanniappan Gopalakrishnan},
  journal={journal of applied pharmaceutical science},
  year={2014},
  volume={4},
  pages={006-011}
}
Peroxisome Proliferator-Activated Receptor gamma (PPARγ) is a nuclear receptor family transcription factor that is expressed in several types of cancers. Antiproliferative and proapoptotic actions of PPARγ agonists suggesting that, it could be a promising therapeutic target for the treatment of variety of cancers. Therefore, the main aim of this study is attempt to identify the novel PPARγ agonist from presence of bioactive compounds in ethanolic extract of Cayratia trifolia using GC-MS… 
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27 Citations
Background Citations
7
Methods Citations
2

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27 Citations

CXCR 4 Inhibitory Activity Analysis of Linoleic Acid Isolated from Ethanolic Extract of Cayratia trifolia ( L . ) : An Molecular Docking Simulation
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The isolated compound of linoleic acid may act as novel inhibitor aginst CXCR4 and further it can be lead to development of therapeutic agent for variety of cancers and other disorders.
1-Pentacosanol Isolated from Stem Ethanolic Extract of Cayratia trifolia (L.) is A Potential Target for Prostate Cancer-In SILICO Approach
Cayratia trifolia (L.) are the traditional medicinal plants used in the Indian Ayurvedic system of medicine. The main objective of the study was to isolate and characterize the structure and function…
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TLDR
These screened natural compounds from E. crispa leaves may serve as potential inhibitors for HER2 and they might lead to development of new therapeutic agents against cancer and its associated complications.
Analysis of Novel C-X-C Chemokine Receptor Type 4 (CXCR4) Inhibitors from Hexane Extract of Euclea crispa (Thunb.) Leaves by Chemical Fingerprint Identification and Molecular Docking Analysis
TLDR
These screened natural compounds from E. crispa leaves may serve as potential inhibitors for CXCR4 and they might leads to development of new therapeutic agents against cancer and its associated complications.
IN SILICO SCREENING OF POTENT PPARGAMMA AGONISTS AMONG NATURAL ANTICANCER COMPOUNDS OF INDIAN ORIGIN
TLDR
A better understanding of the intermolecular interactions of these compounds with peroxisome proliferator-activated receptor gamma (PPARγ) is essential, as its activity is reported in many of the cancers involving colon, breast, gastric, and lung.
Dietary Evaluation , Antioxidant and Cytotoxic Activity of Crude Extract from Chia Seeds ( Salvia hispanica L . ) against Human Prostate Cancer Cell Line ( PC-3 )
TLDR
The crude extract of Chia seeds can be used as a therapeutic option in prostate cancer cells, however, further studies are warranted to substantiate the current findings.
CHROMATOGRAPHIC AND SPECTROPHOTOMETRIC ANALYSIS OF BIOACTIVE COMPOUNDS FROM CAYRATIA TRIFOLIA (L.) STEM
Objective: The present study was to analyze the bioactive compounds from stem ethanolic extract of Cayratia trifolia by FTIR, HPTLC and GC-MS techniques. Methods: The FTIR was applied and infrared…
Anti-inflammatory activity screening of Kalanchoe pinnata methanol extract and its validation using a computational simulation approach
Chromatographic Fingerprinting Analysis of Secondary Metabolites Present in Ethanolic Extract of Tabernaemontana divaricata (L.) R. Br. by HPTLC Technique
Abstract Tabernaemontana divaricata (L.) R. Br is a medicinal plant which is blongs to the family of Apocyanaceae, the whole plant extract possess many biological activities such as antioxidant…
Antioxidant and antimicrobial activities of (6E, 10E)-2, 6, 24-trimethyl pentacosa-2, 6, 10-triene from Euclea crispa leaves
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