Identification of nodal metastases in melanoma using sox-10.

  title={Identification of nodal metastases in melanoma using sox-10.},
  author={Charay D Jennings and Jinah Kim},
  journal={The American Journal of dermatopathology},
  volume={33 5},
The presence of S100-positive dendritic cells hinders the identification of isolated melanoma tumor cells and micrometastases in sentinel lymph nodes. Sox-10, a transcription factor that plays an important role in schwannian and melanocytic cell development, is not expressed in dendritic cells. We investigated the diagnostic utility of Sox-10 in the… CONTINUE READING