Identification of nobiletin, a polymethoxyflavonoid, as an enhancer of adiponectin secretion.

Abstract

Adiponectin, an adipocyte-derived protein with insulin-sensitizing, anti-diabetic and anti-atherogenic activities, is known to be induced during adipocyte differentiation. Nobiletin, a citrus polymethoxy flavonoid, was found to induce the differentiation of ST-13 preadipocytes into mature adipocytes and enhance the production of adiponectin protein at a… (More)
DOI: 10.1016/j.bmcl.2009.02.002

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