Identification of nine human-specific frameshift mutations by comparative analysis of the human and the chimpanzee genome sequences

  title={Identification of nine human-specific frameshift mutations by comparative analysis of the human and the chimpanzee genome sequences},
  author={Y. Hahn and B. Lee},
  volume={21 Suppl 1},
  • Y. Hahn, B. Lee
  • Published 2005
  • Biology, Medicine, Computer Science
  • Bioinformatics
  • MOTIVATION The recent release of the draft sequence of the chimpanzee genome is an invaluable resource for finding genome-wide genetic differences that might explain phenotypic differences between humans and chimpanzees. AVAILABILITY In this paper, we describe a simple procedure to identify potential human-specific frameshift mutations that occurred after the divergence of human and chimpanzee. The procedure involves collecting human coding exons bearing insertions or deletions compared with… CONTINUE READING
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