Identification of new tumor suppressor genes in triple-negative breast cancer.

Abstract

Although genomic sequencing has provided a better understating of the genetic landmarks in triple-negative breast cancer (TNBC), functional validation of candidate cancer genes (CCG) remains unsolved. In this study, we used a transposon mutagenesis strategy based on a two-step Sleeping Beauty (SB) forward genetic screen to identify and validate new tumor… (More)
DOI: 10.1158/0008-5472.CAN-17-0785

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