Identification of new derivatives of sinigrin and glucotropaeolin produced by the human digestive microflora using 1H NMR spectroscopy analysis of in vitro incubations.

@article{Combourieu2001IdentificationON,
  title={Identification of new derivatives of sinigrin and glucotropaeolin produced by the human digestive microflora using 1H NMR spectroscopy analysis of in vitro incubations.},
  author={Bruno Combourieu and Lila Elfoul and A. M. Delort and Sylvie Rabot},
  journal={Drug metabolism and disposition: the biological fate of chemicals},
  year={2001},
  volume={29 11},
  pages={
          1440-5
        }
}
One- and two-dimensional (1)H NMR spectroscopy were used to study the biotransformation of two dietary glucosinolates, sinigrin (SIN), and glucotropaeolin (GTL) by the human digestive microflora in vitro. The molecular structures of the new metabolites issued from the aglycone moiety of the glucosinolate were identified, and the modulation of carbon metabolism was studied by quantifying bacterial metabolites issued from the xenobiotic incubation in the presence or absence of a source of free… CONTINUE READING

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