Identification of naïve HCV-1 patients with chronic hepatitis who may benefit from dual therapy with peg-interferon and ribavirin.

@article{Andriulli2014IdentificationON,
  title={Identification of na{\"i}ve HCV-1 patients with chronic hepatitis who may benefit from dual therapy with peg-interferon and ribavirin.},
  author={Angelo Andriulli and Vito Di Marco and Maurizio Margaglione and Antonio Massimo Ippolito and Giovanna Fattovich and Antonina Smedile and Maria Rosa Valvano and Vincenza Calvaruso and Domenica Gioffreda and Michele Milella and Filomena Morisco and Martina Felder and Giuseppina Brancaccio and Massimo Fasano and Pietro Gatti and Paolo Tundo and Michele Barone and Raffaele Cozzolongo and Mario Angelico and G D'andrea and Nicola Andriulli and Maria Lorena Abate and Giuseppe Mazzella and Giovanni Battista Gaeta and Antonio Crax{\`i} and Teresa Santantonio},
  journal={Journal of hepatology},
  year={2014},
  volume={60 1},
  pages={16-21}
}
BACKGROUND & AIMS The pool of HCV genotype 1 patients likely to be cured by peg-interferon and ribavirin remains to be quantified. METHODS In 1045 patients treated with peg-interferon and ribavirin, two therapeutic strategies were confronted: the first one evaluated only baseline variables associated with sustained virological response (SVR), and the second one included the rapid virologic response (RVR) in addition to baseline predictors. An 80% SVR rate was the threshold to retain a… CONTINUE READING

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