Identification of multiple sites suitable for insertion of foreign genes in herpes simplex virus genomes.

@article{Morimoto2009IdentificationOM,
  title={Identification of multiple sites suitable for insertion of foreign genes in herpes simplex virus genomes.},
  author={Tomomi Morimoto and Jun Arii and Hiroomi Akashi and Yasushi Kawaguchi},
  journal={Microbiology and immunology},
  year={2009},
  volume={53 3},
  pages={155-61}
}
Information on sites in HSV genomes at which foreign gene(s) can be inserted without disrupting viral genes or affecting properties of the parental virus are important for basic research on HSV and development of HSV-based vectors for human therapy. The intergenic region between HSV-1 UL3 and UL4 genes has been reported to satisfy the requirements for such… CONTINUE READING