Identification of mokB involved in monacolin K biosynthesis in Monascus pilosus

Abstract

Monacolin K (MK), which is widely used as an antihypercholesterolemia medicine, is produced as a fungal secondary metabolite through the polyketide pathway. The MK biosynthetic gene cluster proposed for Monascus pilosus BCRC38072 was also identified in M. pilosus NBRC4480. The mokB gene, located at the end of the putative gene cluster and possibly encoding… (More)
DOI: 10.1007/s10529-009-0093-3

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@article{Sakai2009IdentificationOM, title={Identification of mokB involved in monacolin K biosynthesis in Monascus pilosus}, author={Kanae Sakai and Hiroshi Kinoshita and Takuya Nihira}, journal={Biotechnology Letters}, year={2009}, volume={31}, pages={1911-1916} }