Identification of mitochondrial F(1)F(0)-ATP synthase interacting with galectin-3 in colon cancer cells.

@article{Kim2008IdentificationOM,
  title={Identification of mitochondrial F(1)F(0)-ATP synthase interacting with galectin-3 in colon cancer cells.},
  author={Duck-Woo Kim and Kyung Hee Kim and Byong Chul Yoo and Sung-Hye Hong and Yong Chul Lim and Y Shin and J L Park},
  journal={Cancer science},
  year={2008},
  volume={99 10},
  pages={1884-91}
}
To evaluate the effect of galectin-3 in cell cycle regulation of colon cancer cells, we looked for binding molecules interacting with galectin-3 and examined the changes in cell cycle by suppressing galectin-3 and the binding molecule. To identify target molecules interacting with galectin-3, we analyzed immunoprecipitate of the anti-galectin-3 antibody obtained from human colon cancer cell line, using matrix-assisted laser desorption ionization-mass spectrometry. We validated subcellular… CONTINUE READING

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