Identification of microRNAs involved in acute rejection and spontaneous tolerance in murine hepatic allografts

@article{Morita2014IdentificationOM,
  title={Identification of microRNAs involved in acute rejection and spontaneous tolerance in murine hepatic allografts},
  author={Miwa Morita and Jiajie Chen and Masayuki Fujino and Yusuke Kitazawa and Atsushi Sugioka and Liang Zhong and Xiao‐Kang Li},
  journal={Scientific Reports},
  year={2014},
  volume={4}
}
Graft acceptance without the need for immunosuppressive drugs is the ultimate goal of transplantation therapy. In murine liver transplantation, allografts are accepted across major histocompatibility antigen complex barriers without the use of immunosuppressive drugs and constitute a suitable model for research on immunological rejection and tolerance. MicroRNA (miRNA) has been known to be involved in the immunological responses. In order to identify mRNAs in spontaneous liver allograft… 
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