Identification of mammalian aspartate-4-decarboxylase.

@article{Rathod1985IdentificationOM,
  title={Identification of mammalian aspartate-4-decarboxylase.},
  author={P. Rathod and J. H. Fellman},
  journal={Archives of biochemistry and biophysics},
  year={1985},
  volume={238 2},
  pages={
          435-46
        }
}
  • P. Rathod, J. H. Fellman
  • Published 1985
  • Chemistry, Medicine
  • Archives of biochemistry and biophysics
    • Several animal tissues were examined for aspartate-4-decarboxylase (EC 4.1.1.12) activity. Highest activity was seen in murine livers, in rodent livers, and in rodent kidneys. The rat liver enzyme was membrane associated and could be solubilized and partially purified with the aid of detergents. The purification studies, and studies on the stoichiometry and kinetics of the reaction, showed that aspartate is directly converted to alanine. Such a metabolic reaction had not been reported before in… CONTINUE READING
    View on PubMed
    doi.org
    11 Citations
    Highly Influencial Citations
    1
    Background Citations
    4
    11 Citations
    Citation Type

    Citation Type

    Regulation of mammalian aspartate-4-decarboxylase: its possible role in oxaloacetate and energy metabolism.
    • 6
    The possible role of a bacterial aspartate β-decarboxylase in the biosynthesis of alamandine.
    • 1
    Molecular cloning of the aspartate 4-decarboxylase gene from Pseudomonas sp. ATCC 19121 and characterization of the bifunctional recombinant enzyme
    • N. Wang, C. Lee
    • Biology, Medicine
    • Applied Microbiology and Biotechnology
    • 2006
    • 14
    Asparagine catabolism in rat liver mitochondria.
    • 9
    Insights into the mechanism of Pseudomonas dacunhae aspartate beta-decarboxylase from rapid-scanning stopped-flow kinetics.
    • 8
    Controlling reaction specificity in pyridoxal phosphate enzymes.
    • M. Toney
    • Chemistry, Medicine
    • Biochimica et biophysica acta
    • 2011
    • 115
    • PDF
    Amino Acids and Nitrogen Compounds
    • 5
    The role of mitochondria in sulfolipid biosynthesis by Euglena chloroplasts
    • 15
    Profiling the orphan enzymes
    • 37
    In silico atomic tracing by substrate-product relationships in Escherichia coli intermediary metabolism.
    • M. Arita
    • Biology, Medicine
    • Genome research
    • 2003
    • 110
    • Highly Influenced
    • PDF

    References

    SHOWING 1-10 OF 21 REFERENCES
    Regulation of mammalian aspartate-4-decarboxylase: its possible role in oxaloacetate and energy metabolism.
    • 6
    Purification and properties of L-Aspartate-alpha-decarboxylase, an enzyme that catalyzes the formation of beta-alanine in Escherichia coli.
    • 107
    Intermediary metabolism of L-cysteinesulfinic acid in animal tissues.
    • 76
    Identification of pyruvate in S-adenosylmethionine decarboxylase from rat liver.
    • 38
    • PDF
    Cysteine sulfinate transamination activity of aspartate aminotransferases.
    • 33
    Identification of bound pyruvate essential for the activity of phosphatidylserine decarboxylase of Escherichia coli.
    • 49
    Cysteinesulfinate metabolism. altered partitioning between transamination and decarboxylation following administration of beta-methyleneaspartate.
    • O. Griffith
    • Medicine, Chemistry
    • The Journal of biological chemistry
    • 1983
    • 81
    The metabolism of taurine to isethionate.
    • 40
    Electrofocusing of integral membrane proteins in mixtures of zwitterionic and nonionic detergents.
    • 59
    Protein measurement with the Folin phenol reagent.
    • 274,635