Identification of malaria retinopathy improves the specificity of the clinical diagnosis of cerebral malaria: findings from a prospective cohort study.

@article{Birbeck2010IdentificationOM,
  title={Identification of malaria retinopathy improves the specificity of the clinical diagnosis of cerebral malaria: findings from a prospective cohort study.},
  author={Gretchen Lano Birbeck and Nicholas A. V. Beare and S. Lewallen and S. J. Glover and Malcolm Edward Molyneux and Peter Wolfe Kaplan and Terrie E. Taylor},
  journal={The American journal of tropical medicine and hygiene},
  year={2010},
  volume={82 2},
  pages={231-4}
}
The diagnosis of cerebral malaria (CM) is difficult to confirm in endemic regions with limited neurodiagnostics. Accurate diagnoses are critical for trials and outcomes studies. Findings from an autopsy-based study suggest that identifying malaria retinopathy in children satisfying the standard clinical case definition of CM improves our ability to accurately diagnose CM in vivo. In a post hoc analysis of a prospective exposure-control study to evaluate CM as a risk factor for epilepsy, we… CONTINUE READING

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