Identification of low responders to a 300-mg clopidogrel loading dose in patients undergoing coronary stenting.

@article{Angiolillo2005IdentificationOL,
  title={Identification of low responders to a 300-mg clopidogrel loading dose in patients undergoing coronary stenting.},
  author={Dominick Joseph Angiolillo and Antonio Fern{\'a}ndez-Ort{\'i}z and Esther Bernardo and Celia Ram{\'i}rez and Carlos Felipe Barrera-Ram{\'i}rez and Manel Sabat{\'e} and R. Caballero Hern{\'a}ndez and Ra{\'u}l Moreno and Javier Escaned and Fernando Alfonso and Cami{\~n}o Ba{\~n}uelos and Marco A. Costa and Theodore A. Bass and Carlos M Macaya},
  journal={Thrombosis research},
  year={2005},
  volume={115 1-2},
  pages={101-8}
}
BACKGROUND Although patients undergoing coronary stenting routinely receive dual antiplatelet treatment to reduce the risk of stent thrombosis, this undesired event still occurs. A suboptimal response to clopidogrel treatment (low responders) has been suggested to contribute to stent thrombosis. In the present study, platelet function profiles were assessed in patients undergoing coronary stenting receiving a standard 300-mg clopidogrel loading dose with the aim to identify low clopidogrel… CONTINUE READING

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