Identification of lineage-specific zygotic transcripts in early Caenorhabditis elegans embryos.

@article{Robertson2004IdentificationOL,
  title={Identification of lineage-specific zygotic transcripts in early Caenorhabditis elegans embryos.},
  author={S. R. M. Robertson and Premnath Shetty and Rueyling Lin},
  journal={Developmental biology},
  year={2004},
  volume={276 2},
  pages={
          493-507
        }
}
During Caenorhabditis elegans embryogenesis, a maternally supplied transcription factor, SKN-1, is required for the specification of the mesendodermal precursor, EMS, in the 4-cell stage embryo. When EMS divides, it gives rise to a mesoderm-restricted precursor, MS, and an endoderm-restricted precursor, E. To systematically identify genes that function as key regulators of MS and/or E-derived tissues, we identified, by microarray analyses, genes that are newly transcribed within a short… CONTINUE READING
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