Identification of known and novel genes in activated monocytes from patients with rheumatoid arthritis.

@article{Stuhlmueller2000IdentificationOK,
  title={Identification of known and novel genes in activated monocytes from patients with rheumatoid arthritis.},
  author={Bruno Stuhlmueller and Uwe Ungethuem and Steffen Scholze and L. Cabrales Mart{\'i}nez and Marina M. Backhaus and Hans G Kraetsch and Raimund W. Kinne and Gerd R{\"u}diger Burmester},
  journal={Arthritis and rheumatism},
  year={2000},
  volume={43 4},
  pages={
          775-90
        }
}
OBJECTIVE To define gene activation patterns of monocytes (MO) in patients with rheumatoid arthritis (RA). METHODS A complementary DNA (cDNA) library was constructed from first-leukapheresis MO obtained from an RA patient with active disease; 32P-labeled cDNA from first-leukapheresis MO (activated pool) and third-leukapheresis MO (nonactivated pool) were used as probes for differential hybridization. Reverse transcriptase-polymerase chain reaction (RT-PCR) was used to assess gene activation… CONTINUE READING
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