Identification of interleukin-6 as an autocrine growth factor for Epstein-Barr virus-immortalized B cells.

Abstract

Autocrine growth factors are believed to be important for maintenance of an immortalized state by Epstein-Barr virus (EBV), because cell-free supernatants of EBV-immortalized cell lines promote the proliferation of autologous cells and permit their growth at low cell density. In this study, we provide evidence for the existence of two autocrine growth… (More)

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@article{Tosato1990IdentificationOI, title={Identification of interleukin-6 as an autocrine growth factor for Epstein-Barr virus-immortalized B cells.}, author={Giovanna Tosato and Jerome E. Tanner and Karen D. Jones and M. Revel and Sandra E. Pike}, journal={Journal of virology}, year={1990}, volume={64 6}, pages={3033-41} }