Identification of interaction partners of the adapter protein Nck in T cells

Abstract

The adaptor protein Nck almost exclusively consists of one SH2 domain and three SH3 domains and plays an important role in linking receptor tyrosine kinases (and associated proteins) to modulators of the actin cytoskeleton. In T cells, Nck thereby connects T cell receptor signaling to the machinery of actin reorganization thus initiating changes in cell… (More)
DOI: 10.1186/1478-811X-7-S1-A84

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