Identification of inflammatory mediators and their modulation by strategies for the management of the systemic inflammatory response during cardiac surgery.

b v THE SYSTEMIC INFLAMMATORY RESPONSE (manifested by pyrexia, leukocytosis, tachycardia, hypotension, issue fluid accumulation, and organ failure) is generated during ardiac surgery because of processes such as ischemia-reperfusion njury, gut ischemia, and contact activation of cells by the extraorporeal circuit (Fig 1).1-3 The release of inflammatory… CONTINUE READING