Identification of increased genetic risk scores for schizophrenia in treatment-resistant patients

  title={Identification of increased genetic risk scores for schizophrenia in treatment-resistant patients},
  author={Joachim Frank and Martin Lang and Stephanie H. Witt and Jana Strohmaier and Dan Rujescu and Sven Cichon and Franziska Degenhardt and Markus M. N{\"o}then and David A. Collier and Stephan Ripke and D Naber and Marcella Rietschel},
  booktitle={Molecular Psychiatry},
Schizophrenia is a severe neuropsychiatric disorder that affects around 0.5–1% of the population. Research has shown that early intervention increases the likelihood of remission and reduces the severity of symptoms, as well as attenuates the decline in social and overall functioning. Around 30% of patients fail to respond adequately to the usual antipsychotic medications, and are classified as being treatment resistant. These patients can be treated with the atypical antipsychotic clozapine… CONTINUE READING
Highly Cited
This paper has 56 citations. REVIEW CITATIONS
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS


Publications citing this paper.
Showing 1-10 of 24 extracted citations

56 Citations

Citations per Year
Semantic Scholar estimates that this publication has 56 citations based on the available data.

See our FAQ for additional information.

Similar Papers

Loading similar papers…