Identification of immunoreactive epitopes of the Porphyromonas gingivalis heat shock protein in periodontitis and atherosclerosis.

@article{Choi2011IdentificationOI,
  title={Identification of immunoreactive epitopes of the Porphyromonas gingivalis heat shock protein in periodontitis and atherosclerosis.},
  author={J I Choi and S -D Lee and Koanhoi Kim and Bong-Kyu Choi},
  journal={Journal of periodontal research},
  year={2011},
  volume={46 2},
  pages={240-5}
}
BACKGROUND AND OBJECTIVE Heat shock protein 60 (HSP60) of Porphyromonas gingivalis, a major periodontal pathogen, might be a trigger molecule linking infectious periodontitis and autoimmune atherosclerosis. The aim of this study was to identify the peptide specificity of anti-P. gingivalis HSP60 monoclonal antibodies and their cross-reactivity with bacterial and human HSPs. Their specific immunoreactivity to periodontal or atherosclerotic lesions was also investigated. METHODS Twenty patients… CONTINUE READING
Highly Cited
This paper has 40 citations. REVIEW CITATIONS