Identification of immunogenic antigens using a phage-displayed cDNA library from an invasive ductal breast carcinoma tumour.

@article{Hansen2001IdentificationOI,
  title={Identification of immunogenic antigens using a phage-displayed cDNA library from an invasive ductal breast carcinoma tumour.},
  author={Morris H. Hansen and Bj\orn Ostenstad and Mouldy Sioud},
  journal={International journal of oncology},
  year={2001},
  volume={19 6},
  pages={1303-9}
}
The identification of immunogenic antigens for serological testing and vaccine development is a major challenge facing cancer immunology research. To study the humoral immune response in patients with breast cancer, a T7 phage display cDNA library from an invasive ductal breast carcinoma was panned on patient serum IgG antibodies. By monitoring the selection with an immunoscreening technique, positive phage-displayed cDNA products reacting with breast cancer patient IgG antibodies were selected… CONTINUE READING
8 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

Similar Papers

Loading similar papers…