Identification of hybrid-type carbohydrate chains on the light chain of human monoclonal antibody specific to lung adenocarcinoma.

@article{Tachibana1993IdentificationOH,
  title={Identification of hybrid-type carbohydrate chains on the light chain of human monoclonal antibody specific to lung adenocarcinoma.},
  author={Hirofumi Tachibana and Kazutaka Seki and Hiroshi Murakami},
  journal={Biochimica et biophysica acta},
  year={1993},
  volume={1182 3},
  pages={257-63}
}
The carbohydrate chains on the light chains of human monoclonal antibody HB4C5 reactive to human lung adenocarcinoma tissue have been characterized. The HB4C5 antibody consists of two kinds of light chains (30 kDa and 32 kDa). Each chain has different carbohydrates of varying molecular masses linked to the variable regions. The 30 kDa light chain has been confirmed to be the active species for antibody binding. The carbohydrates on the light chains were characterized by lectin blot analysis… CONTINUE READING

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