Identification of human DAN gene, mapping to the putative neuroblastoma tumor suppressor locus.

@article{Enomoto1994IdentificationOH,
  title={Identification of human DAN gene, mapping to the putative neuroblastoma tumor suppressor locus.},
  author={Hiroyuki Enomoto and Toshinori Ozaki and Ei-ichi Takahashi and Nobuo Nomura and Shinji Tabata and Hideyuki Takahashi and Naomi Ohnuma and Mao Tanabe and Junko Iwai and Hideo Yoshida},
  journal={Oncogene},
  year={1994},
  volume={9 10},
  pages={2785-91}
}
The expression of DAN gene (previously designated as N03 gene) is significantly reduced in a variety of transformed rat fibroblasts, including v-src- (SR-3Y1), SV40- and v-mos-transformed 3Y1 cells, compared with that in parental 3Y1 cells. Recently, DAN gene has been shown to possess a tumor suppressive activity when it is overexpressed in SR-3Y1 cells (Ozaki & Sakiyama, 1994). To assess the involvement of DAN gene with human neoplasms, we have isolated human DAN counterpart from a normal lung… CONTINUE READING
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