Identification of homogeneous genetic architecture of multiple genetically correlated traits by block clustering of genome-wide associations.

@article{Gupta2011IdentificationOH,
  title={Identification of homogeneous genetic architecture of multiple genetically correlated traits by block clustering of genome-wide associations.},
  author={Mayetri Gupta and Ching-Lung Cheung and Yi-Hsiang Hsu and Serkalem Demissie and L. Adrienne Cupples and Douglas P Kiel and David Karasik},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={2011},
  volume={26 6},
  pages={1261-71}
}
Genome-wide association studies (GWAS) using high-density genotyping platforms offer an unbiased strategy to identify new candidate genes for osteoporosis. It is imperative to be able to clearly distinguish signal from noise by focusing on the best phenotype in a genetic study. We performed GWAS of multiple phenotypes associated with fractures [bone mineral… CONTINUE READING