Identification of genotypes of hepatitis C virus by sequence comparisons in the core, E1 and NS-5 regions.

@article{Simmonds1994IdentificationOG,
  title={Identification of genotypes of hepatitis C virus by sequence comparisons in the core, E1 and NS-5 regions.},
  author={P. Simmonds and D. B. Smith and F. Mcomish and P. Yap and J. Kolberg and M. Urdea and E. Holmes},
  journal={The Journal of general virology},
  year={1994},
  volume={75 ( Pt 5)},
  pages={
          1053-61
        }
}
Isolates of hepatitis C virus (HCV) show considerable nucleotide sequence variability throughout the genome. Comparisons of complete genome sequences have been used as the basis of classification of HCV into a number of genotypes that show 67 to 77% sequence similarity. In order to investigate whether sequence relationships between genotypes are equivalent in different regions of the genome, we have carried out formal sequence analysis of variants in the 5' non-coding region (5'NCR) and in the… Expand
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Evolutionary analysis of variants of hepatitis C virus found in South-East Asia : comparison with classifications based upon sequence similarity
Variants of hepatit is C virus (HCV) have been classified by nucleotide sequence comparisons in different regions of the genome. Many investigators have defined the ranges of sequence similari tyExpand
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