Identification of genes that are associated with DNA repeats in prokaryotes

@article{Jansen2002IdentificationOG,
  title={Identification of genes that are associated with DNA repeats in prokaryotes},
  author={Ruud Jansen and J. Embden and W. Gaastra and L. Schouls},
  journal={Molecular Microbiology},
  year={2002},
  volume={43}
}
Using in silico analysis we studied a novel family of repetitive DNA sequences that is present among both domains of the prokaryotes (Archaea and Bacteria), but absent from eukaryotes or viruses. This family is characterized by direct repeats, varying in size from 21 to 37 bp, interspaced by similarly sized non‐repetitive sequences. To appreciate their characteri‐stic structure, we will refer to this family as the clustered regularly interspaced short palindromic repeats (CRISPR). In most… Expand
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