Identification of genes for small non-coding RNAs that belong to the regulon of the two-component regulatory system CiaRH in Streptococcus

@inproceedings{Marx2010IdentificationOG,
  title={Identification of genes for small non-coding RNAs that belong to the regulon of the two-component regulatory system CiaRH in Streptococcus},
  author={Patrick Marx and Michael Nuhn and M{\'a}rta Kov{\'a}cs and Regine Hakenbeck and Reinhold Br{\"u}ckner},
  booktitle={BMC Genomics},
  year={2010}
}
Post-transcriptional regulation by small RNAs (sRNAs) in bacteria is now recognized as a wide-spread regulatory mechanism modulating a variety of physiological responses including virulence. In Streptococcus pneumoniae, an important human pathogen, the first sRNAs to be described were found in the regulon of the CiaRH two-component regulatory system. Five of these sRNAs were detected and designated csRNAs for cia-dependent small RNAs. CiaRH pleiotropically affects β-lactam resistance, autolysis… CONTINUE READING
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