Identification of genes expressed in cultures of E. coli lysogens carrying the Shiga toxin-encoding prophage Φ24B

@inproceedings{Riley2011IdentificationOG,
  title={Identification of genes expressed in cultures of E. coli lysogens carrying the Shiga toxin-encoding prophage Φ24B},
  author={Laura M Riley and Marta Veses-Garcia and Jeffrey D. Hillman and Martin Handfield and Alan J. McCarthy and Heather E Allison},
  booktitle={BMC Microbiology},
  year={2011}
}
Shigatoxigenic E. coli are a global and emerging health concern. Shiga toxin, Stx, is encoded on the genome of temperate, lambdoid Stx phages. Genes essential for phage maintenance and replication are encoded on approximately 50% of the genome, while most of the remaining genes are of unknown function nor is it known if these annotated hypothetical genes are even expressed. It is hypothesized that many of the latter have been maintained due to positive selection pressure, and that some… CONTINUE READING

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