Identification of gene expression changes associated with the progression of retinal degeneration in the rd1 mouse.

@article{Hackam2004IdentificationOG,
  title={Identification of gene expression changes associated with the progression of retinal degeneration in the rd1 mouse.},
  author={Abigail S. Hackam and Richelle Strom and Dongmei Liu and Jiang Qian and Chenwei Wang and Deborah C Otteson and Tushara L Gunatilaka and Ronald H Farkas and Itay Chowers and Masaaki Kageyama and Thierry L{\'e}veillard and Jos{\'e}-Alain Sahel and Peter Anthony Campochiaro and Giovanni Parmigiani and Donald J. Zack},
  journal={Investigative ophthalmology & visual science},
  year={2004},
  volume={45 9},
  pages={2929-42}
}
PURPOSE One approach to gaining insight into the biological pathways contributing to rod and cone photoreceptor death is to identify patterns of gene expression changes. In the present study, a custom retinal microarray was developed to analyze the rd1 mouse, a well-characterized animal model of human retinal degeneration. METHODS A microarray was… CONTINUE READING