Identification of gene expression changes induced by chemical allergens in dendritic cells: opportunities for skin sensitization testing.

@article{Gildea2006IdentificationOG,
  title={Identification of gene expression changes induced by chemical allergens in dendritic cells: opportunities for skin sensitization testing.},
  author={Lucy A Gildea and Cindy A. Ryan and Leslie M Foertsch and Jennifer M. Kennedy and Rebecca Jane Dearman and I A N Kimber and G. Frank Gerberick},
  journal={The Journal of investigative dermatology},
  year={2006},
  volume={126 8},
  pages={1813-22}
}
Cellular changes within resident skin dendritic cells (DCs) after allergen uptake and processing are critical events in the acquisition of skin sensitization. Here we describe the development of a set of selection criteria to derive a list of potential target genes from previous microarray analyses of human peripheral blood-derived (peripheral blood mononuclear cells (PBMCs)-DCs) treated with dinitrobenzene sulfonic acid for predicting skin-sensitizing chemicals. Based on those criteria, a… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 23 extracted citations

Similar Papers

Loading similar papers…