Identification of fusB-Mediated Fusidic Acid Resistance Islands in Staphylococcus epidermidis Isolates

  title={Identification of fusB-Mediated Fusidic Acid Resistance Islands in Staphylococcus epidermidis Isolates},
  author={Hsiao-Jan Chen and J. Tsai and W. Hung and S. Tseng and P. Hsueh and L. Teng},
  journal={Antimicrobial Agents and Chemotherapy},
  pages={5842 - 5849}
ABSTRACT To understand the high prevalence of fusB genes in fusidic acid-resistant Staphylococcus epidermidis, analysis of resistance elements in 34 isolates was performed. First, sequence analysis of the aj1-LP-fusB region indicated that at least three types were present. Type I contained full-length aj1, type II contained a partial aj1 truncated from nucleotide position 93 to 421, and type III contained a more truncated aj1 that retained only the last 37 bp. Isolates with type I or type II… Expand
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