Identification of functional promoter elements in the rabbit smooth muscle myosin heavy chain gene.

@article{Katoh1994IdentificationOF,
  title={Identification of functional promoter elements in the rabbit smooth muscle myosin heavy chain gene.},
  author={Youichi Katoh and Evgeny Loukianov and Elizabeth J. Kopras and Alla Zilberman and Muthu Periasamy},
  journal={The Journal of biological chemistry},
  year={1994},
  volume={269 48},
  pages={30538-45}
}
Despite the importance of smooth muscle cell proliferation in vascular pathophysiological states, the mechanisms regulating smooth muscle cell growth and differentiation are poorly understood. Previous studies have shown that adult rabbit smooth muscles express two types of myosin heavy chain (MHC) isoforms, SM1 and SM2, which are generated through alternative RNA splicing from a single smooth muscle MHC (SMHC) gene. In the present study, we isolated and characterized the rabbit SMHC gene… CONTINUE READING
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