Identification of fructose 3-phosphate in the lens of diabetic rats.

@article{Szwergold1990IdentificationOF,
  title={Identification of fructose 3-phosphate in the lens of diabetic rats.},
  author={Benjamin S. Szwergold and Francis Kappler and Truman R. Brown},
  journal={Science},
  year={1990},
  volume={247 4941},
  pages={451-4}
}
Fructose 3-phosphate, a novel monosaccharide phosphate, has been identified in the lens of diabetic rats. This compound, which is not present in normal lenses, is a protein glycosylating agent and enzyme inactivator. In addition, because of its structural features, this metabolite is relatively labile and undergoes hydrolysis to yield inorganic phosphate… CONTINUE READING