Identification of formation of initial native structure in onconase from an unfolded state.

@article{Gahl2012IdentificationOF,
  title={Identification of formation of initial native structure in onconase from an unfolded state.},
  author={Robert F Gahl and Robert E. Oswald and Harold A. Scheraga},
  journal={Biochemistry},
  year={2012},
  volume={51 1},
  pages={521-32}
}
In the oxidative folding of onconase, the stabilization of intermediates early in the folding process gives rise to efficient formation of its biologically active form. To identify the residues responsible for the initial formation of structured intermediates, the transition from an ensemble of unstructured three-disulfide species, 3S(U), to a single… CONTINUE READING