Identification of fibronectin receptors on T lymphocytes

  title={Identification of fibronectin receptors on T lymphocytes},
  author={Pina M. Cardarelli and Michael D. Pierschbacher},
  journal={The Journal of Cell Biology},
  pages={499 - 506}
We report the identification of fibronectin receptors on thymocytes and T lymphoma cells. Affinity chromatography of extracts of the T cell lymphoma, WR16.1, on a fibronectin-Sepharose column combined with specific elution using a synthetic peptide containing the cell attachment-promoting sequence, arginine-glycine-aspartic acid, yielded two polypeptide components having apparent molecular masses of approximately 160 kD reduced and 175 and 150 kD nonreduced. Immunoprecipitations from surface… CONTINUE READING


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