Identification of errors introduced during high throughput sequencing of the T cell receptor repertoire

@inproceedings{Nguyen2010IdentificationOE,
  title={Identification of errors introduced during high throughput sequencing of the T cell receptor repertoire},
  author={Phuong Nguyen and Jing Ma and Deqing Pei and Caroline A. Obert and Cheng Cheng and Terrence L Geiger},
  booktitle={BMC Genomics},
  year={2010}
}
Recent advances in massively parallel sequencing have increased the depth at which T cell receptor (TCR) repertoires can be probed by >3log10, allowing for saturation sequencing of immune repertoires. The resolution of this sequencing is dependent on its accuracy, and direct assessments of the errors formed during high throughput repertoire analyses are… CONTINUE READING