Identification of epitopes within the circumsporozoite protein of Plasmodium vivax recognized by murine T lymphocytes.

@article{Rodrigues1991IdentificationOE,
  title={Identification of epitopes within the circumsporozoite protein of Plasmodium vivax recognized by murine T lymphocytes.},
  author={M. C. Martins Rodrigues and A. C. M. Paiva and Ana Paula Barzan Dutra and Nobuko Yoshida and Cl{\'o}vis Ryuichi Nakaie},
  journal={Experimental parasitology},
  year={1991},
  volume={72 3},
  pages={271-7}
}
The murine cellular immune response to the circumsporozoite (CS) protein of Plasmodium vivax was characterized using five synthetic peptides, some of which we identified as corresponding to T cell epitopes. The peptides P308-320, P344-355 and P353-364 were immunogenic, inducing a genetically restricted proliferative response, due to the activation of CD4+ T… CONTINUE READING