Identification of enolase as a laminin-binding protein on the surface of Staphylococcus aureus.

@article{Carneiro2004IdentificationOE,
  title={Identification of enolase as a laminin-binding protein on the surface of Staphylococcus aureus.},
  author={C{\'e}lia Regina Whitaker Carneiro and Edilberto Post{\'o}l and Regina Nomizo and Luiz Fernando Lima Reis and Ricardo Renzo Brentani},
  journal={Microbes and infection},
  year={2004},
  volume={6 6},
  pages={604-8}
}
We have previously demonstrated that Staphylococcus aureus, a highly invasive bacteria, presents a 52-kDa surface protein that mediates its binding to laminin. In order to better characterize this receptor, we excised this putative laminin receptor from two-dimensional (2-D) PAGE and used it as antigen for raising a mouse hyperimmune serum which was for screening an S. aureus expression library. A single clone of 0.3 kb was obtained, and its sequence revealed 100% homology with S. aureus alpha… CONTINUE READING

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