Identification of endogenous reference genes for qRT-PCR analysis in normal matched breast tumor tissues.

@article{GurDedeoglu2009IdentificationOE,
  title={Identification of endogenous reference genes for qRT-PCR analysis in normal matched breast tumor tissues.},
  author={Bala Gur-Dedeoglu and Ozlen Konu and Betul Bozkurt and Gulusan Ergul and Selda Seçkin and Isik G. Yulug},
  journal={Oncology research},
  year={2009},
  volume={17 8},
  pages={
          353-65
        }
}
Quantitative gene expression measurements from tumor tissue are frequently compared with matched normal and/or adjacent tumor tissue expression for diagnostic marker gene selection as well as assessment of the degree of transcriptional deregulation in cancer. Selection of an appropriate reference gene (RG) or an RG panel, which varies depending on cancer type, molecular subtypes, and the normal tissues used for interindividual calibration, is crucial for the accurate quantification of gene… CONTINUE READING
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