Identification of endogenous acyl amino acids based on a targeted lipidomics approach.

@article{Tan2010IdentificationOE,
  title={Identification of endogenous acyl amino acids based on a targeted lipidomics approach.},
  author={Bo Tan and David K. O'Dell and Yun William Yu and M Francesca Monn and H. Velocity Hughes and Sumner H. Burstein and John Michael Walker},
  journal={Journal of lipid research},
  year={2010},
  volume={51 1},
  pages={
          112-9
        }
}
Using a partially purified bovine brain extract, our lab identified three novel endogenous acyl amino acids in mammalian tissues. The presence of numerous amino acids in the body and their ability to form amides with several saturated and unsaturated fatty acids indicated the potential existence of a large number of heretofore unidentified acyl amino acids. Reports of several additional acyl amino acids that activate G-protein coupled receptors (e.g., N-arachidonoyl glycine, N-arachidonoyl… CONTINUE READING
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