Identification of endocrine-disrupting effects in aquatic vertebrates and invertebrates: report from the European IDEA project.

  title={Identification of endocrine-disrupting effects in aquatic vertebrates and invertebrates: report from the European IDEA project.},
  author={Helmut Segner and K Caroll and Martina Fenske and Colin R. Janssen and Gerd Maack and David Pascoe and Christoph Schaefers and Gert F Vandenbergh and Meagan Watts and Alexander Wenzel},
  journal={Ecotoxicology and environmental safety},
  volume={54 3},
The EU-funded project IDEA aimed to evaluate (a) what parameters and endpoints allow the detection of endocrine-mediated developmental and reproductive effects of (xeno)estrogens in life cycle- and life stage-specific toxicity tests with the zebrafish Danio rerio, a small laboratory fish used in many ecotoxicity test guidelines, and (b) whether substances that act as estrogens in vertebrates may also adversely affect the development, differentiation, and reproduction of aquatic invertebrates… CONTINUE READING
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Development and validation of a homologous zebrafish (Danio rerio hamilton-buchanan) vitellogenin enzyme-linked immunosorbent assay (ELISA) and its application for studies on estrogenic chemicals

  • M. Fenske, R. van Aerle, S. Brack, C. R. Tyler, H. Segner
  • Comp. Biochem. Physiol
  • 2001
Highly Influential
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Development of a reproductive performance test for endocrine disrupting chemicals using pairbreeding fathead minnows (Pimephales promelas)

  • J. E. Harries, T. Runnalls, +4 authors C. R. Tyler
  • Environ. Sci. Technol
  • 2000
Highly Influential
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OECD activity on endocrine disrupters test guidelines development

  • M. C. Huet
  • Ecotoxicology
  • 2000
Highly Influential
16 Excerpts

The endocrine disruptor screening program developed by the US Environmental Protection Agency

  • P. A. Fenner-Crisp, A. F. Maciorowski, G. E. Timm
  • Ecotoxicology
  • 2000
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Effects of 17aethinylestradiol on sexual development of the amphipod Hyalella azteca

  • G. F. Vandenbergh, D. Adriaens, C. R. Janssen
  • Ecotoxicol. Environ. Saf
  • 2002
2 Excerpts

Morphological development of the gonads in the zebrafish

  • G. Maack, H. Segner
  • Danio rerio. J. Fish Biol.,
  • 2002
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