Identification of diverse full-length endogenous betaretroviruses in megabats and microbats

  title={Identification of diverse full-length endogenous betaretroviruses in megabats and microbats},
  author={Joshua A Hayward and Mary Tachedjian and Jie Cui and Hume Ernest Field and Edward C. Holmes and Lin-fa Wang and Gilda Tachedjian},
Betaretroviruses infect a wide range of species including primates, rodents, ruminants, and marsupials. They exist in both endogenous and exogenous forms and are implicated in animal diseases such as lung cancer in sheep, and in human disease, with members of the human endogenous retrovirus-K (HERV-K) group of endogenous betaretroviruses (βERVs) associated with human cancers and autoimmune diseases. To improve our understanding of betaretroviruses in an evolutionarily distinct host species, we… CONTINUE READING


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