Identification of distinct prognostic subgroups in low- and intermediate-1-risk myelodysplastic syndromes by flow cytometry.

@article{Loosdrecht2007IdentificationOD,
  title={Identification of distinct prognostic subgroups in low- and intermediate-1-risk myelodysplastic syndromes by flow cytometry.},
  author={Arjan A. van de Loosdrecht and Theresia M. Westers and August H Westra and Angelika M. Dr{\"a}ger and Vincent H J van der Velden and Gert Jan Ossenkoppele},
  journal={Blood},
  year={2007},
  volume={111 3},
  pages={
          1067-77
        }
}
The World Health Organization (WHO) classification contributes to refined classification and prognostication of myelodysplastic syndromes (MDSs). Flow cytometry might add significantly to diagnostic and prognostic criteria. Our analysis of bone marrow samples from 50 patients with MDS showed aberrant expression of differentiation antigens in the myelomonocytic lineage. This also accounted for refractory anemia (RA) with or without ringed sideroblasts (RS), indicating multilineage dysplasia. In… CONTINUE READING

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