Identification of distinct and common gene expression changes after oxidative stress and gamma and ultraviolet radiation.

@article{Heinloth2003IdentificationOD,
  title={Identification of distinct and common gene expression changes after oxidative stress and gamma and ultraviolet radiation.},
  author={Alexandra N. Heinloth and Rodney E. Shackelford and Cynthia L. Innes and Lee Bennett and LePing Li and Rupesh P Amin and Stella Sieber and Kristina G. Flores and Pierre R. Bushel and Richard S. Paules},
  journal={Molecular carcinogenesis},
  year={2003},
  volume={37 2},
  pages={65-82}
}
The human genome is exposed to many different kinds of DNA-damaging agents. While most damage is detected and repaired through complex damage recognition and repair machineries, some damage has the potential to escape these mechanisms. Unrepaired DNA damage can give rise to alterations and mutations in the genome in an individual cell, which can result in malignant transformation, especially when critical genes are deregulated. In this study, we investigated gene expression changes in response… CONTINUE READING